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产品目录

Caspase 8/CASP8抗体图片
产品货号:
Z32844
中文名称:
Caspase 8/CASP8抗体
英文名称:
Anti-Caspase 8/CASP8 Antibody (Clone#2G12)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Caspase 8/CASP8 Antibody (Clone#2G12)
指标别名Apoptotic protease Mch 5;Casp 8;CASP8;Caspase 8;Caspase 8/p18;Caspase 8/p43/p18;caspase8;FADD like ICE;FLICE;ICE like apoptotic protease 5;MCH5
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC
基因名称CASP8
克隆号2G12
抗体来源Mouse
抗体类型IgG
免疫原Recombinant Protein
计算分子量55KD
成分Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
纯化方式The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料CASP8 is also known as CAP4,MACH or MCH5.This gene encodes a member of the cysteine-aspartic acid protease (caspase) family.Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.Caspases exist as inactive proenzymes composed of a prodomain,a large protease subunit,and a small protease subunit.Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits.This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli.The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD.In addtion,this protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls,which implicated the role in neurodegenerative diseases.Many alternatively spliced transcript variants encoding different isoforms have been described,although not all variants have had their full-length sequences determined.
Uniprot IDQ14790
基因名全称Caspase-8
蛋白名全称Caspase-8
推荐稀释比WB 1:1000~2000
IHC1:200~500

相关搜索:Caspase 8/CASP8抗体Caspase 8抗体CASP8单抗Anti-Caspase 8/CASP8 Antibody (Clone#2G12)
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